Table III.

Grade 3–5 adverse events.

Adverse event	Grade 3 (%)	Grade 4 (%)	Grade 5 (%)	Grade 3–5 (%)
Infection	3 (21)	0	0	3 (21)
Febrile neutropenia	2 (14)	0	0	2 (14)
Neutropenia	0	2 (14)	0	2 (14)
Syncope	2 (14)	0	0	2 (14)
Hypotension	2 (14)	0	0	2 (14)
Hypertension	1 (7)	0	0	1 (7)
Angina pectoris	1 (7)	0	0	1 (7)
Atrial fibrillation	1 (7)	0	0	1 (7)
PML	1 (7)	0	0	1 (7)
Haemorrhage	0	0	1 (7)	1 (7)
Decreased LOC	1 (7)	0	0	1 (7)
Thrombocytosis	0	1 (7)	0	1 (7)
Thrombocytopenia	1 (7)	0	0	1 (7)
Hypophosphataemia	1 (7)	0	0	1 (7)

LOC, level of consciousness; PML, progressive multifocal leucoencephalopathy.