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EBV-induced proliferation and Ig production in human peripheral blood B cells by EBV. To measure proliferation and antibody production rate, EBV-infected (closed symbols) or mock-infected (open symbols) B cells from a single donor were distributed at a density of 1×105/well in microculture wells containing irradiated PBMC as feeder cells. (A) The 24-h[3H]thymidine incorporation; (B) IgM, IgG, IgA, and IgD concentrations in the culture supernatants.
