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. 2016 Feb 1;37(3):649–658. doi: 10.3892/ijmm.2016.2477

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Copyright: © Kim et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of Lycii Radicis Cortex (LRC) on the trabecular area and bone loss in rats which underwent an ovariectomy; histological examination of tissue sections from the femoral heads of rats using H&E staining. Femurs of each group were captured using a light microscope. (A) Representative femoral heads (histological staining). Scale bar, 500 μm. (B) Sham-operated rats, (C) ovariectomized (OVX) rats, (D) rats which were orally administered estradiol, (E) rats which were orally administered 5 mg/kg LRC (LRC-L), (F) rats which were orally administered 50 mg/kg LRC (LRC-H). Scale bar, 200 μm. (G) Trabecular area was measured using ImageJ software. Data are represented as the means ± SEM of eight independent experiments. ^##p<0.01 compared with sham-operated group; ^**p<0.01 and ^*p<0.05 compared with OVX.