Table II.
Animal group | Endocrine cell type
|
|||||
---|---|---|---|---|---|---|
CgA | Serotonin | PYY | Enteroglucagon | PP | Somatostatin | |
Control | 119.0±16.5 | 39.9±4.4 | 96.0±1.2 | 43.1±3.2 | 60.7±2.8 | 43.1±2.8 |
DSS | 300.6±27.7a | 62.6±5.8a | 120.5±5.9b | 87.2±7.2a | 41.5±2.8a | 28.3±2.2c |
DSS-G | 146.7±22.4 | 35.9±4.9 | 98.2±7.0 | 51.3±3.6 | 65.8±4.4 | 40.7±2.7 |
DSS-Q | 136.6±12.2 | 36.2±4.3 | 84.8±2.0 | 49.5±2.9 | 59.1±3.5 | 46.7±3.8 |
Data are the mean ± SEM values DSS, dextran sodium sulfate; DTCM-G, 3-[(dodecylthiocarbonyl)-methyl]-glutarimide; DHME-Q, dehydroxy-methylepoxyquinomicin; CgA, chromogranin A; PYY, peptide YY; PP, pancreatic polypeptide.
P<0.0001,
P<0.01 and
P<0.05 vs. controls.