Table 1.
Differentially expressed extracellular matrix genes by LBECs.
| DEV vs. CON | |||
|---|---|---|---|
| Gene ID | Gene Name | p-value | Regulation |
| LUM | lumican | 0.01378 | DOWN |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | 0.01618 | DOWN |
| ADAMTS4 | ADAM metallopeptidase with thrombospondin 1 motif 4 |
0.02168 | UP |
| MMP1 | matrix metallopeptidase 1 (interstitial collagenase) | 0.03815 | DOWN |
| OG1 vs. CON | |||
| Gene ID | Gene Name | p-value | Regulation |
| SDCBP | syndecan binding protein (syntenin) | 0.00001 | UP |
| BGN | biglycan | 0.00008 | DOWN |
| VIM | vimentin | 0.00023 | DOWN |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00119 | DOWN |
| THBS2 | thrombospondin 2 | 0.00217 | DOWN |
| FMOD | fibromodulin | 0.00519 | DOWN |
| DCN | decorin | 0.00788 | DOWN |
| MMP3 | matrix metallopeptidase 3 (stromelysin 1) | 0.00899 | UP |
| SCX | scleraxis | 0.01447 | DOWN |
| ADAMTS4 | ADAM metallopeptidase with thrombospondin 1 motif 4 |
0.02755 | UP |
| MMP13 | matrix metallopeptidase 13 (collagenase 3) | 0.0283 | UP |
| COL14A1 | collagen, type XIV, alpha 1 | 0.0342 | DOWN |
| TIMP1 | TIMP metallopeptidase inhibitor | 0.04343 | UP |
| OG1 vs. DEV | |||
| Gene ID | Gene Name | p-value | Regulation |
| SCX | scleraxis | 0.00058 | DOWN |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00075 | DOWN |
| MMP1 | matrix metallopeptidase 1 (interstitial collagenase) | 0.00193 | UP |
| SDCBP | syndecan binding protein (syntenin) | 0.00717 | UP |
| THBS2 | thrombospondin 2 | 0.00941 | DOWN |
| MMP3 | matrix metallopeptidase 3 (stromelysin 1) | 0.01159 | UP |
| BGN | biglycan | 0.01753 | DOWN |
| MMP13 | matrix metallopeptidase 13 (collagenase 3) | 0.03645 | UP |
| TIMP1 | TIMP metallopeptidase inhibitor | 0.04087 | UP |