Table 2.
Selected differentially expressed inflammatory genes by LBECs.
| CON vs. DEV | |||
|---|---|---|---|
| Gene ID | Gene Name | p-value | Regulation |
| HRH4 | histamine receptor H4 | 0.01384 | UP |
| LITAF | lipopolysaccharide-induced TNF factor | 0.02014 | UP |
| CON vs. OG1 | |||
| Gene ID | Gene Name | p-value | Regulation |
| IL4R | interleukin 4 receptor | 0.00013 | UP |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (COX1) | 0.00068 | DOWN |
| PTGES | prostaglandin-E synthase | 0.00244 | UP |
| TLR2 | toll-like receptor 2 | 0.00360 | UP |
| BD-1 | beta-defensin-1 | 0.00417 | UP |
| PTGFR | prostaglandin F receptor | 0.00564 | UP |
| SOCS3 | suppressor of cytokine signalling 3 | 0.00598 | UP |
| C1QTNF7 | C1q and tumour necrosis factor related protein 7 | 0.00677 | DOWN |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.01138 | UP |
| CXCL2 | chemokine (C-X-C motif) ligand 2; MIP-2a | 0.01543 | UP |
| IL1RN | interleukin 1 receptor antagonist | 0.01946 | UP |
| PLA2G4A | phospholipase A2, group IVA | 0.01957 | UP |
| CCL2 | chemokine (C-C motif) ligand 2; MCP-1 | 0.01962 | UP |
| CASP1 | caspase1; interleukin1 beta-converting enzyme | 0.02133 | UP |
| CCR2 | chemokine (C-C motif) receptor 2; MCP-1 receptor | 0.02309 | DOWN |
| IL12B | interleukin 12b; IL-12 p40 | 0.02400 | UP |
| TLR4 | toll-like receptor 4 | 0.02567 | UP |
| TNFSF12 | tumour necrosis factor (ligand) superfamily, member 12 | 0.02628 | DOWN |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.02632 | UP |
| SELE | E-selectin | 0.02935 | UP |
| TNFRSF13c | tumour necrosis factor receptor superfamily, member 13c | 0.03033 | DOWN |
| SPLA2 | secretory phopholipase A2 | 0.03126 | UP |
| PTGS2 | Prostaglandin-endoperoxide synthase 2 (COX-2) | 0.03191 | UP |
| CCL8 | chemokine (C-C motif) ligand 8; MCP-2 | 0.03455 | UP |
| SAA1 | serum amyloid A1 | 0.03895 | UP |
| CCL13 | chemokine (C-C motif) ligand 13 (MCP-4) | 0.03948 | UP |
| OG1 vs DEV | |||
| Gene ID | Gene Name | p-value | Regulation |
| iNOS | inducible nitic oxide synthase | 0.00009 | DOWN |
| PTGES | prostaglandin E synthase | 0.00291 | UP |
| TLR2 | toll-like receptor 2 | 0.00389 | UP |
| PTGFR | prostaglandin F receptor | 0.00429 | UP |
| BD-1 | beta-defensin-1 | 0.00644 | UP |
| C1QTNF7 | C1q and tumour necrosis factor related protein 7 | 0.01107 | DOWN |
| CASP1 | caspase1; interleukin1 beta-converting enzyme | 0.01287 | UP |
| IL1R1 | interleukin-1 receptor antagonist | 0.01288 | UP |
| CSF3 | colony stimulating factor 3 (granulocyte) | 0.01759 | DOWN |
| LITAF | lipopolysaccharide-induced TNF factor | 0.02018 | DOWN |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.02046 | UP |
| IL-6 | interleukin-6 | 0.02774 | UP |
| SOCS3 | suppressor of cytokine signaling 3 | 0.03521 | UP |
| CCL13 | chemokine (C-C motif) ligand 13 (MCP-4) | 0.03576 | UP |
| SPLA2 | secretory phopholipase A2 | 0.03864 | UP |
| TLR4 | toll-like receptor 4 | 0.04020 | UP |
| CD14 | CD14 molecule | 0.04172 | UP |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (COX2) | 0.04633 | UP |
| CCL2 | chemokine (C-C motif) ligand 2 (MCP-1) | 0.04951 | UP |