TABLE 1.
Bacterial differences observed between villin-TLR4 and WT littermates at various taxonomic levelsa
| Phylum | Class | Order | Family | Genus |
|---|---|---|---|---|
| Firmicutes (↑) | Clostridia (↑) | Lactobacillales (↓) | ||
| Clostridiales (↑) | Lachnospiraceae (↑+) | 94otu1346 (↑) | ||
| 94otu19924 (↑+) | ||||
| Blautia (+) | ||||
| Ruminococcaceae (↑) | 94otu11945 (↑) | |||
| Faecalibacterium (↑) | ||||
| Mogibacteriaceae (↑) | ||||
| 91otu5089 (↓) | ||||
| Veillonellaceae | Dialister (+) | |||
| Phascolarctobacterium (↑) | ||||
| Bacteroidetes | Flavobacteria (↓) | Flavobacteriales (↓) | ||
| Proteobacteria (↓) | Gammaproteobacteria (↓) | Enterobacteriales (↓) | Enterobacteriaceae (↓) | |
| Pseudomonadales (↓) | ||||
| Betaproteobacteria (−) | Burkholderiales (−) | |||
| Alphaproteobacteria | Rhodospirillales (↓) | |||
| Actinobacteria | Coriobacteria (↓+) | Coriobacteriales (↓+) | Coriobacteriaceae (↑) | |
| Fusobacteria (↓) | Fusobacteria (↓) | Fusobacteriales (↓) | Fusobacteriaceae (↓) | Fusobacterium (↓) |
a
The symbol ↑ or ↓ indicates an increase or decrease in villin-TLR4 mucosa relative to WT mucosa. The symbol + or − indicates an increase or decrease in villin-TLR4 lumen relative to WT lumen. Bold indicates a significant difference in presence or absence between the two groups (P < 0.05; FDR, <0.1). Underlining indicates a significant difference in relative abundance between the two groups (P < 0.05; FDR, <0.1).