TABLE 2.

Differentially expressed immune response genes^a

Gene	4496ΔPPI1 mutant vs strain 4496
	Fold change	Significance
Il10	3.5	***
Itgam	3.4	*
Ly96	2.5	*
Lyz2	−2.45	*
RorC	−2.08	**
Tlr4	2.33	*

^aExpression levels of innate and adaptive immune response genes in the lungs of mice at 6 h postchallenge with the 4496ΔPPI1 or 4496 strain were assayed by PCR array as described in Materials and Methods. Data represent fold change in expression between 4496ΔPPI1 mutant-infected and strain 4496-infected mice. A positive value indicates higher expression in the mutant than in the wild type; a negative value indicates higher expression in the wild type than in the mutant. Only genes with statistically significant differences in expression are shown. *, P < 0.05; **, P < 0.01; ***, P < 0.001 (as determined by software provided by Qiagen).