TABLE 3.
Roles of ptsG and cyaB in tick colonization and transmission of B. burgdorferi from ticks to mice
| Strain (mutated gene) | Insertion ratio | Unfed ticks |
Fed ticks |
Mouse infection by tick transmission |
|||
|---|---|---|---|---|---|---|---|
| No. of positive cultures/total | Mean no. of spirochetes per field ± SD | No. of positive cultures/total | Mean no. of spirochetes per field ± SD | No. of positive cultures/total (no. of positive mice/total) | No. of mice with positive serology/total | ||
| 5A18NP1 | 7/10 | 0.05 ± 0.06 | 15/15 | 4.5 ± 4.1 | 12/12 (3/3) | 3/3 | |
| T11TC373 (cyaB) | 0.02 | 10/10 | 0.14 ± 0.15 | 17/17 | 3.3 ± 1.7 | 12/12 (3/3) | 3/3 |
| T08TC498 (cyaB) | 0.93 | 7/10 | 0.04 ± 0.04 | 20/22 | 1.2 ± 0.9 | 12/12 (3/3) | 3/3 |
| T10TC291 (ptsG) | 0.45 | 10/10 | 0.13 ± 0.12 | 22/22 | 3.9 ± 3.8 | 0/12 (0/3) | 0/3 |
| ptsG::pKFSS1-ptsG | 9/10 | 0.08 ± 0.07 | 23/23 | 6.3 ± 6.7 | 4/12 (1/3) | 1/3 | |