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. 2016 Feb 24;10:799–810. doi: 10.2147/DDDT.S99670

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© 2016 Guo et al. This work is published and licensed by Dove Medical Press Limited

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Representative micrographs of kidney tissue stained with periodic acid–Schiff.

Notes: Arrows show the thickened basement membrane. (A) NC group, (B) DC group, (C) Met group, (D) TSD-40 group, (E) TSD-80 group, (F) TSD-160 group, (G) glomerular volume, and (H) expansion of matrix index. Values are presented as mean ± SD for eight rats in each group. ^ΔΔP<0.01 as compared with the normal control group. ^#P<0.05 as compared with the diabetic control group. ^##P<0.01 as compared with the diabetic control group.

Abbreviations: NC, normal control group; DC, diabetic control group; Met, metformin hydrochloride group; TSD, total saponin of Dioscorea hypoglaucae Palibin.