Table 2.

Multivariable analysis using Cox proportional hazard modeling to examine factors predicting the development of complications following radical prostatectomy

	Treatment-related hospital admission			Minimally invasive urologic procedures			Open surgical procedures
	HR	95% CI	p value	HR	95% CI	p value	HR	95% CI	p value
Age (>60 years vs. <60 years)	1.20	1.10–1.30	<0.0001	1.19	1.12–1.26	<0.0001	1.18	0.79–1.75	0.4278
Comorbidity (Total ADG)	1.08	1.06–1.10	<0.0001	1.08	1.06–1.09	<0.0001	1.11	1.02–1.20	0.0175
Surgeon volume (RP/year)
≤15	Referent			Referent			Referent
15–23	0.85	0.77–0.94	0.0018	0.97	0.90–1.04	0.3366	0.87	0.53–1.44	0.5940
24–38	0.74	0.67–0.82	<0.0001	0.77	0.71–−0.83	<0.0001	0.71	0.42–1.19	0.1908
≥39	0.54	0.47–0.61	<0.0001	0.69	0.64–0.75	<0.0001	0.83	0.47–1.45	0.5041
LHIN population density
<26	Referent			Referent			Referent
44–85	0.48	0.41–0.56	<0.0001	0.85	0.77–0.95	0.0038	0.31	0.17–0.57	0.0002
97–324	0.94	0.82–1.07	0.3452	1.10	0.99–1.22	0.0796	0.42	0.24–0.75	0.0030
>549	1.06	0.92–1.21	0.4333	1.30	1.18–1.45	<0.0001	0.58	0.33–1.03	0.0610
Hospital setting (community vs. academic)	0.75	0.67–0.83	<0.0001	0.94	0.88–1.01	0.1010	0.87	0.54–1.39	0.5502

ADG: aggregated disease groups; CI: confidence interval; HR: hazard ratio; RP: radical prostatectomy.