Table 1. Details of the Loci and haplotypes in the MTHFR gene.
| Locus 1 | Locus 2 | Locus 3 | Locus 4 | ||
| Selected tag SNP | C677T | A1298C | — | — | |
| dbSNP ID | rs1801133 | rs1801131 | rs9651118 | rs1476413 | |
| Allele | C/T | A/C | T/C | G/A | |
| Peptide allele | A/V222 | E429A | intron | intron | |
| Positionb (bp) | 11,778,965 | 11,177,742 | 11,796,480 | 11,786,566 | |
| MAF † | 0.364 | 0.178 | 0.422 | 0.205 | |
| Haplotype | Frequency | ||||
| #1 | T | A | T | G | 0.39906 |
| #2 | C | A | C | G | 0.32846 |
| #3 | C | C | T | A | 0.18728 |
| #4 | C | A | T | G | 0.05451 |
| #5 | T | A | C | G | 0.01072 |
| #6 | C | C | T | G | 0.01006 |
| #7 | C | A | C | A | 0.00432 |
| #8 | C | C | C | A | 0.00427 |
| #9 | T | A | C | A | 0.00133 |
† MAF : Minor allele frequency from the International HapMap Database