Table 1.
SCOT-HEART and PROMISE: Trial characteristics.
| SCOT-HEART | PROMISE | |
|---|---|---|
| Country | UK | United States and Canada |
| Comparators | CCTA + standard of care vs. standard of care | CCTA vs. functional stress test |
| Trial design | Open-label | Open-label |
| Recruiting centers | 12 | 193 |
| Length of follow-up | 20 months | 25 months |
| Sample size | 4,146 | 10,003 |
| Primary endpoint | Certainty of diagnosis of angina due to coronary heart disease | Death, nonfatal MI, hospitalization for unstable angina, major procedural complications (anaphylaxis, stroke, major bleeding, and renal failure) |
| Follow-up | National Health Record systems | Mail and telephone |
CCTA = cardiac computed tomography angiography; MI = myocardial infarction.