Table 3.
Pooled OR of the OGG1 Ser326Cys polymorphism based on different types of cancer
Type of cancer | No. of studies | Case/Control | Dominant model | Recessive model | Homozygous model | |||
---|---|---|---|---|---|---|---|---|
OR (95 % CI) | Pa | OR (95 % CI) | Pa | OR (95 % CI) | Pa | |||
Head and neck | 6 | 1479/1589 | 1.3 (0.99–1.73) | <0.05* | 1.37 (1.09–1.73) | 0.007* | 1.69 (1.06–2.68) | 0.02* |
Gastric | 3 | 450/908 | 0.9 (0.71–1.14) | 0.39 | 0.78 (0.47–1.29) | 0.34 | 0.76 (0.45–1.27) | 0.3 |
Colorectal | 5 | 2479/3130 | 1.29 (0.9–1.84) | 0.15 | 1.34 (1.05–1.71) | 0.01* | 1.38 (1.08–1.77) | 0.009* |
aP heterogeneity
* Significant at P < 0.05