Table 1.

Metabolic Profile in WT and Hexim1 HT Mice HFD

	WT	HT	WT-HFD	HT-HFD
	n = 10	n = 10	n = 8	n = 8
Body weight (g)	31 ± 0.4	29.1 ± 0.3	44.1 ± 0.8	35.7 ± 1.2b
Glucose (mg/dL)	129 ± 5.8	108 ± 4.4	231 ± 8.3	126 ± 8.8b
Insulin (ng/mL)	0.38 ± 0.08	0.4 ± 0.02	1.36 ± 0.2	0.4 ± 0.05b
HOMA-IR	2.2 ± 1.3	1.9 ± 0.6	14 ± 3.0	2.2 ± 0.4b
Cholesterol (mg/dL)	77 ± 7.0	86 ± 9.4	201 ± 11.7c	200 ± 10.5b,d
Triglycerides (mg/dL)	36.0 ± 3.1	51 ± 5.6a	62 ± 3.2c	47 ± 2.7b
Leptin (ng/mL)	2.1 ± 0.2	3.6 ± 0.4a	4.8 ± 0.6	6.7 ± 0.7b
Adiponectin (ng/mL)	4.2 ± 0.4	6.7 ± 0.6a	5.3 ± 0.2	7.1 ± 0.3b
Adipocyte cell size (μm2)	6892 ± 558	5470 ± 386	15 397 ± 1029	9015 ± 760b
Triglycerides (mg/mg protein)	40 ± 5.0	26 ± 1.0	66.2 ± 5.7	38.2 ± 8.4b

Values are the mean ± SEM for each group. HOMA-IR, homeostasis model assessment of insulin resistance.

^aP < .05 vs WT mice.

^bP < .05 vs WT-HFD mice

^cP < .05 vs WT mice.

^dP < .05 vs HT mice.