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Peak INa block.
| Peak INa block | n | |
|---|---|---|
| Wild-type | ||
| zNaV1.5 | ||
| AMD 0.5 μM | 0.05 ± 0.11 | 3 |
| AMD 2.5 μM | 0.14 ± 0.12 | 6 |
| DES 0.5 μM | 0.32 ± 0.05 | 7 |
| DES 2.5 μM | 0.12 ± 0.13 | 6 |
| ΔKPQ | ||
| NaV1.5 | ||
| AMD 0.5 μM | 0.39 ± 0.12 | 6 |
| AMD 2.5 μM | 0.38 ± 0.28 | 4 |
| DES 0.5 μM | 0.28 ± 0.04 | 4 |
| DES 2.5 μM | 0.55 ± 0.12 | 6 |
