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Ramp INa.
| Ramp INa | n | |
|---|---|---|
| Wild-type | ||
| NaV1.5 | ||
| Control | 1.77 ± 0.25 | 19 |
| AMD 0.5 μM | 2.51 ± 0.62 | 5 |
| AMD 2.5 μM | 3.10 ± 1.02 | 4 |
| DES 0.5 μM | 1.28 ± 0.57 | 6 |
| DES 2.5 μM | 3.52 ± 0.91 | 4 |
| ΔKPQ | ||
| NaV1.5 | ||
| Control | 4.30 ± 0.47 | 22 |
| AMD 0.5 μM | 1.84 ± 0.82 | 5 |
| AMD 2.5 μM | 3.39 ± 0.69 | 5 |
| DES 0.5 μM | 6.27 ± 1.28 | 6 |
| DES 2.5 μM | 7.18 ± 1.45 | 5 |
