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. 2016 Feb 29;594(5):1247–1264. doi: 10.1113/JP271091

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© 2016 The Authors. Experimental Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Values are mean ± SEM for the change from baseline in oxygen and glucose delivery in the ascending and the descending aorta and the ratio of these values in fetal sheep undergoing normoxic (◯, n = 6) or chronic hypoxic (, n = 6) pregnancy. (N), normoxic recovery. The x‐axis shows time in hours (hr) and days (d). Significant differences (P < 0.05): *differences indicating a significant main effect of time compared with baseline; ^†differences indicating a significant main effect of treatment compared with normoxic pregnancy (two‐way repeated‐measures ANOVA + Tukey test). For the ratio of ascending/descending oxygen delivery, the two‐way ANOVA represents an analysis of the area under the curve.

Inline graphic — Values are mean ± SEM for the change from baseline in oxygen and glucose delivery in the ascending and the descending aorta and the ratio of these values in fetal sheep undergoing normoxic (◯, n = 6) or chronic hypoxic (, n = 6) pregnancy. (N), normoxic recovery. The x‐axis shows time in hours (hr) and days (d). Significant differences (P < 0.05): *differences indicating a significant main effect of time compared with baseline; ^†differences indicating a significant main effect of treatment compared with normoxic pregnancy (two‐way repeated‐measures ANOVA + Tukey test). For the ratio of ascending/descending oxygen delivery, the two‐way ANOVA represents an analysis of the area under the curve.