Table 3.

Acute hypoxic ventilatory responses of Phd2^+/− versus Phd2^+/−;Hif‐1α^+/− mice or Phd2^+/− versus Phd2^+/−;Hif‐2α^+/− mice

	Hypoxic ventilatory response (ml min−1 g−1)
Acute hypoxic stimulus	Phd2+/−	Phd2+/−;Hif‐1α+/−	P value
10% O2/3% CO2	6.21 ± 0.81	5.61 ± 0.49	0.54
10% O2	2.04 ± 0.64	1.29 ± 0.38	0.33
	Phd2+/−	Phd2+/−;Hif‐2α+/−
10% O2/3% CO2	5.58 ± 0.83	3.17 ± 0.46	0.03
10% O2	2.97 ± 0.73	1.26 ± 0.45	0.07

Values shown are mean changes in minute ventilation (± SEM) in response to the indicated acute hypoxic stimulus; n = 7 littermate pairs for each genotype; P < 0.05 highlighted in bold type.