Table 3. Visual analog scale (VAS) for the cold test according to gender at baseline and at four weeks and six weeks in the control (n=42) and test (n=40) groups.

Gender  VAS for the cold test	Observation periods			P-valuea)
	Baseline	4 wk	6 wk
Male
Test group (n=10)	6.30±1.44	4.10±2.48b)	2.30±2.07b,c)
Change from baseline		-2.20±1.92	-4.00±1.65d)	<0.01
Control group (n=7)	4.60±2.02	2.71±1.63b)	2.93±2.05b)
Change from baseline		-1.88±0.68	-1.67±1.21
Female
Test group (n=30)	6.32±1.84	4.82±2.33b)	4.33±2.28b)
Change from baseline		-1.50±1.61	-1.99±1.83	0.26
Control group (n=35)	6.24±1.88	4.60±2.08b)	3.71±1.79b,c)
Change from baseline		-1.64±1.85	-2.53±1.96

Values are presented as mean±standard deviation.

n, number of patients.

^a) P-value for repeated measures analysis of variance.

^b)Statistically significant difference from baseline in each group (paired t-test, P<0.05).

^c)Statistically significant difference from the four-week values in each group (paired t-test, P<0.05).

^d)Statistically significant difference in the change from baseline compared to the control group (paired t-test, P<0.05).