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. 2016 Feb 16;2016:7067259. doi: 10.1155/2016/7067259

Figure 4.

Figure 4

Serial 99mTc-MDP bone scans in methylprednisolone treated rabbits. Animals from Figure 3 were scanned with 99mTc-MDP, two days prior to 99mTc-Annexin V imaging. (a) Abnormal 99mTc-MDP is found by 8 weeks, as indicated by the arrow. (b) A significant increase in 99mTc-MDP is observed only at 8 weeks after methylprednisolone exposure, P < 0.01 at 8 weeks versus the rest of the time points. There were no significant differences in 99mTc-MDP uptake between pretherapy (week 0) and 5 or 6 weeks.