Table 2.
Clinical and biological data of patients with or without ZG hyperplasia.
| Variable | Patients with ZG hyperplasia (n = 21) | Patients without ZG hyperplasia (n = 8) | P value |
|---|---|---|---|
| Preoperative baseline, PAC, pg/mL | 658 (421–1236)# | 537 (387–879)# | NS |
| Postoperative baseline, PAC, pg/mL | 329 (153–567) | 27 (12–57) | <0.01 |
| Preoperative baseline, PRA, ng/mL·h−1 | 0.1 (0.1–0.2)# | 0.1 (0.0–0.4)# | NS |
| Postoperative baseline, PRA, ng/mL·h−1 | 1.2 (1.0–2.4) | 2.7 (0.7–5.2) | <0.01 |
| Preoperative baseline, ARR, pg/mL per ng/mL·h−1 | 488.2 (194.4–785.3)# | 768.6 (235.1–5452)# | NS |
| Postoperative baseline, RR, pg/mL per ng/mL·h−1 | 126.5 (78.5–359.7) | 4.5 (1.2–21.2) | <0.01 |
| Preoperative-urinary, aldosterone, µg/24 h | 24.0 (19.3–40.2) | 40.6 (26.9–54.4)# | NS |
| Postoperative-urinary, aldosterone, µg/24 h | 16.8 (8.5–28.1) | 6.38 (1.0–14.6) | <0.05 |
| Diameter, cm | 1.6 (1.2–2.4) | 1.8 (1.3–2.4) | NS |
| Preoperative SBP, mmHg | 167.6 ± 13.7# | 167.9 ± 21.2∗ | NS |
| Postoperative SBP, mmHg | 145.2 ± 7.5 | 123.6 ± 13.1 | <0.01 |
| Preoperative DBP, mmHg | 101.6 ± 8.6# | 95.9 ± 7.7∗ | NS |
| Postoperative DBP, mmHg | 94.7 ± 7.1 | 82.9 ± 5.5 | <0.01 |
| Preoperative serum K+, mmol/L | 3.0 ± 0.5# | 2.8 ± 0.3∗ | <0.05 |
| Postoperative serum K+, mmol/L | 3.8 ± 0.3 | 3.87 ± 0.24 | NS |
| SBP decline, mmHg | 22.4 ± 13.1 | 44.25 ± 16.4 | <0.01 |
| DBP decline, mmHg | 7.0 ± 11.8 | 13.0 ± 8.8 | NS |
| Serum K+ rise, mmol/L | 0.7 ± 0.5 | 1.1 ± 0.3 | <0.05 |
PAC, plasma aldosterone concentration; PRA, plasma renin activity; ARR, aldosterone-to-renin ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure. Data are given as mean ± SD or median (interquartile range), as appropriate. # P < 0.05 preoperatively versus postoperatively in patients with ZG hyperplasia; ∗ P < 0.05 preoperatively versus postoperatively in patients without ZG hyperplasia.