Table 1.
Comparison of prodromal state diagnostic criteria
Ultra–high-risk | Criteria of Prodromal States (COPS) | ||
Attenuated positive symptom criteria | Attenuated positive symptom criteria | ||
The presence of one or more of the following symptoms: ideas of reference, odd beliefs or magical thinking, paranoid ideation, perceptual disturbance, and odd behavior and appearance of sufficient severity based on the Brief Psychiatric Rating Scale (a rating of 2 or 3 on suspiciousness or unusual thought content scale, 1 or 2 on the hallucinations scale, or 1 to 3 on conceptual disorganization scale) held with some conviction based on rating with the Comprehensive Assessment of Symptoms and History |
The presence of one or more of the following symptoms: unusual thought content, suspiciousness, grandiose ideas, perceptual abnormalities, or disorganized communication of sufficient severity (2 to 5), based on the Scale of Prodromal Symptoms rating scale |
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At least one symptom must have been present at least 1 week and not longer than 5 years |
At least one symptom must have begun or significantly worsened during the past year |
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At least one symptom must occur at a frequency of at least several times per week |
At least one symptom must occur at a frequency of once per week |
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Brief limited intermittent psychotic symptoms (BLIP) | Brief intermittent psychotic symptoms | ||
The presence of one or more of the following symptoms: ideas of reference, odd beliefs or magical thinking, paranoid ideation, perceptual disturbance, and odd behavior and appearance of sufficient severity based on the Brief Psychiatric Rating Scale (a rating of 4 or greater on suspiciousness or unusual thought content scale, 3 or greater on hallucinations scale, or 4 or greater on conceptual disorganization scale) held with strong conviction based on rating with the Comprehensive Assessment of Symptoms and History |
The presence of one or more of the following symptoms: unusual thought content, suspiciousness, grandiose ideas, perceptual abnormalities, or disorganized communication at psychotic severity (6), based on the Scale of Prodromal Symptoms rating scale |
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The BLIP occurred in the past year | The symptom must have begun or significantly worsened in the past 3 months |
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The duration of the episode is less than 1 week and symptoms resolved spontaneously |
The symptom must be present for several minutes a day at least once per month |
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Trait and state | Genetic risk and deterioration | ||
Schizotypal personality disorder or a first-degree relative with a psychotic disorder |
Schizotypal personality disorder or a first-degree relative with a psychotic disorder |
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Significant decrease in mental state or functioning for at least 1 month and not longer than 5 years (Global Assessment of Functioning of <30 points from premorbid level); the decrease in functioning occurred within the past year |
At least a 30% drop in Global Assessment of Functioning score for at least 1 month in the past 12 months, and the current Global Assessment of Functioning is 90% less than the highest Global Assessment of Functioning in the past year |