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. 2016 Feb 16;14(2):36. doi: 10.3390/md14020036

Table 1.

Comparison of the IC50 values generated from this study with that from patch clamp.

Compounds IC50 (μM) (95% CI) Patch-Clamp IC50 (μM) Reference
SKA-19 2.02 (1.49–4.74) 5.8 [28]
Riluzole 3.58 (2.67–4.80) 2 [29]
Phenytoin 18.7 (11.8–29.7) 31.6 [24]
Lamotrigine 66.3 (40.6–108.1) 79 [30]
Carbamazepine 77.7 (49.9–121.0) 101 [30]
Lidocaine 150.6 (92.9–244.0) 110 [31]