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. 2016 Mar 1;6:22231. doi: 10.1038/srep22231

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Copyright © 2016, Macmillan Publishers Limited

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(A) Areas of improvement of gray matter volume (GMV) in SLE patients after disease control included bilateral superior frontal gyrus, left middle frontal gyrus, right supplementary motor area, right precentral gyrus and right postcentral gyrus (p < 0.001 uncorrected with minimum cluster size of 980 voxels). (B) Scatterplot of significant Spearman correlation between changes in gray matter volume and SLEDAI after attainment of low SLE disease activity in SLE patients. Abbreviations: MFG = middle frontal gyrus, SFG = superior frontal gyrus, SFG(orb) = superior frontal gyrus (orbital part), SMA = supplementary motor area, PreCG = precentral gyrus, PostCG = postcentral gyrus, SFG = superior frontal gyrus, SLEDAI = Systemic Lupus Erythematosus Disease Activity Index, L = left side, l = left, r = right.