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. 2016 Mar 1;6:22264. doi: 10.1038/srep22264

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Copyright © 2016, Macmillan Publishers Limited

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Increasing growth rates require more efficient protein, assuming a fixed enzyme pool , resulting in the feasible region . The enzymes involved in the utilization of ethanol and acetate have low calculated efficiency, and therefore the maximum growth rate is predicted to be low. For glucose and galactose the gradual shift towards fermentation at high growth rates increases the protein efficiency and thereby the predicted maximum growth rate. Predicted rates are compared with experimentally observed growth rates¹ (▾), acetate 0.11 (0.17), ethanol 0.14 (0.13), galactose 0.28 (0.28) and glucose 0.41 (0.41) h⁻¹.

Inline graphic — Increasing growth rates require more efficient protein, assuming a fixed enzyme pool , resulting in the feasible region . The enzymes involved in the utilization of ethanol and acetate have low calculated efficiency, and therefore the maximum growth rate is predicted to be low. For glucose and galactose the gradual shift towards fermentation at high growth rates increases the protein efficiency and thereby the predicted maximum growth rate. Predicted rates are compared with experimentally observed growth rates¹ (▾), acetate 0.11 (0.17), ethanol 0.14 (0.13), galactose 0.28 (0.28) and glucose 0.41 (0.41) h⁻¹.