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. 2016 Mar 1;6:22326. doi: 10.1038/srep22326

Table 2. Subgroups of patients according to the pre- and post-treatment serum LDH levels.

  Cases (n) Pretreatment serum LDH (IU/L)
Post-treatment serum LDH (IU/L)
Clinical stage* (%)
P#
Mean ± SD Median Range   Median Range I II III IV
Group 1 1309 168.6 ± 28.9 166.0 84.0–245.0 153.5 ± 29.1 151.0 16.0–244.0 62 (4.7%) 260 (19.9%) 634 (48.4%) 353 (27.0%) 0.025
Group 2 83 307.6 ± 87.7 274.0 246.0–753.0 176.9 ± 34.9 174.0 110.0–243.0 0 (0.0%) 11 (13.3%) 33 (39.8%) 39 (47.0%)  
Group 3 28 183.9 ± 26.8 191.5 140.0–241.0 285.4 ± 51.7 269.0 247.0–475.0 1 (3.0%) 5 (17.9%) 13 (46.4%) 9 (32.1%)  
Group 4 8 367.3 ± 134.5 313.0 251.0–565.0 508.7 ± 517.5 271.0 245.0–1756.0 0 (0%) 1 (12.5%) 4 (50%) 3 (37.5%)  

LDH, lactate dehydrogenase; IU, international unit.

*According to the American Joint Committee on Cancer, 7th edition.

#P values were calculated using the chi-square test.