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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Hum Mutat. 2011 Dec 20;33(2):440–447. doi: 10.1002/humu.21662

Figure 5. Effect of putative missense mutations in SCRIB on subcellular localisation.

Figure 5

(a) Protein localisation in MDCK cells: Top - immunofluorescence with anti-GFP (green) and anti-SCRIB (red); Bottom - anti-GFP alone. (b) Quantitative analysis of protein localisation for GFP +ve cells were scored scored as cytoplasmic only, plasma membrane (PM) and cytoplasmic combined, or PM only. ** Statistically significant differences of % cytoplasmic and % PM compared with wild-type (p < 0.001) were determined by two-way analysis of variance.