Skip to main content
. 2016 Jan 27;13(2):166. doi: 10.3390/ijerph13020166

Table 4.

Biomarkers of fibrogenesis.

Marker Abbreviation Components in Combination
Connective tissue derived peptides
 Aminopropeptide of procollagen type III PIIINP
 Aminopropeptide of procollagen type I PINP
 Carboxypropeptide of procollagen type I PICP
 Carboxyterminal telopeptide of type I collagen ICTP
 Hyaluronic acid HA
 β-Crosslaps β-CTX
 Tissue inhibitor of matrix metalloproteinase TIMP
Combination markers
 Fibrotest GGT, ALT, α-2-macroglobulin, haptoglobin, apo A1, bilirubin
 Enhanced liver fibrosis ELF PIIINP, hyaluronic acid, TIMP
 AST/platelet ratio APRI AST, platelet count
 Traffic light test TLT PIIINP, hyaluronic acid, thrombocytes