. 2016 Mar;147(3):273–288. doi: 10.1085/jgp.201511488

Table 1.

Set of parameters of MC16SM used for simulation of multicellular networks

Gate/Parameter	A	V₀	γ_open	γ_closed	R_open	R_closed	P_t	Π
	mV⁻¹	mV	pS	pS	mV	mV
Fast gate	0.15	40	24	3	10,000	10,000	0.00005	−1
Slow gate	0.15	40	24	0	10,000	-	0.00005	−1

The set of parameters of an MC16SM used for simulation of multicellular networks interconnected through electrical synapses formed of GJ channels resembling Cx36 and to assemble Figs. 3 B, 4 (E–G), 5, 6, 7, and 8. In search of minimum g_j necessary for synchronization and signal transfer of APs in 1-D and 2-D clusters of neurons (g_j,min-synch and g_j,min-transf; Fig. 5), we varied the number of GJ channels forming electrical synapses.