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. 2016 Mar;147(3):243–254. doi: 10.1085/jgp.201511525

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© 2016 McMahon et al.

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Figure 6. — Endogenous Ca²⁺ buffering capacity (κ_e) is reduced during the ∼10 min of whole-cell recording. Open circles show κ_e shortly after break in. After 10 min of dialysis (open triangles), a significant fraction of the endogenous buffering capacity was lost. Smooth curves show the model fits from trains collected at the relevant time points.