Table 1.
Patient characteristics. The p-value stems from the Mann-Whitney-U-Test and for sex and valve morphology from the Chi-Square-Test.
| Parameter | AS | Healthy | p-value |
|---|---|---|---|
| n | 37 | 37 | |
| Sex (male | female) | 23 | 14 | 20 | 17 | 0.48 |
| Age (y) | 63 ± 13 | 60 ± 10 | 0.042* |
| Height (cm) | 169 ± 9 | 171 ± 13 | 0.25 |
| Weight (kg) | 83 ± 13 | 79 ± 17 | 0.074 |
| BMI (kg/m2) | 28.8 ± 4.3 | 27.7 ± 10.3 | 0.005* |
| BSA (m2) | 1.97 ± 0.19 | 1.92 ± 0.21 | 0.22 |
| Systolic blood pressure (mmHg) | 140 ± 15 | 134 ± 13 | 0.012* |
| Diastolic blood pressure (mmHg) | 83 ± 14 | 82 ± 10 | 0.84 |
| Heart rate (min−1) | 67 ± 12 | 68 ± 9 | 0.77 |
| Aortic diameter (mm) | 35 ± 7 | 32 ± 3 | 0.016* |
| Aortic orifice area (cm2) | 1.5 ± 0.6 | 3.5 ± 0.5 | <0.001* |
| Aortic orifice area index (cm2/m2) | 0.75 ± 0.33 | 1.85 ± 0.25 | <0.001* |
| Morphology of aortic valve (tricuspid | bicuspid) | 21 | 16 | 37 | 0 | <0.001* |
| LV-EF (%) | 66 ± 6 | 63 ± 5 | 0.062 |
| LV-SV-Index (ml/m2) | 44 ± 11 | 48 ± 8 | 0.044* |
| LV-EDV-Index (ml/cm) | 0.77 ± 0.18 | 0.87 ± 0.18 | 0.020* |
| LV-Mass-Index (g/cm) | 0.94 ± 0.30 | 0.70 ± 0.15 | <0.001* |
| Relative Wall Mass (g/ml) | 1.25 ± 0.38 | 0.81 ± 0.13 | <0.001* |
*
p<0.05