Table 4.
Ratio.3 vs 0 | Map | Gene | Description |
---|---|---|---|
Up-regulated genes | |||
5.71 | 3q12.1 | ESDN | Endothelial and smooth muscle cell-derived neuropilin-like protein |
5.55 | 3q21 | MYLK | “Myosin, light polypeptide kinase” |
4.43 | 3p22-p21.3 | CCK | Cholecystokinin |
4.21 | 3q25.1-q26.1 | SMARCA3 | “SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 3” |
4.18 | 3q13 | PVRL3 | Poliovirus receptor-related 3 |
3.38 | 3p26 | BHLHB2 | “Basic helix-loop-helix domain containing, class B, 2” |
3.23 | 3p21-p14 | PTPRG | “Protein tyrosine phosphatase, receptor type, G” |
3.17 | 3p21 | SCN5A | “Sodium channel, voltage-gated, type V, α polypeptide [long (electrocardiographic) QT syndrome 3]” |
3.10 | 3q23 | RBP1 | “Retinol binding protein 1, cellular” |
2.65 | 3q26.2-q26.3 | CLDN11 | Claudin 11 (oligodendrocyte transmembrane protein) |
2.50 | 3q26.2 | SERPINI1 | “Serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1” |
2.44 | 3p14.3-p14.2 | ADAMTS9 | “A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9” |
2.38 | 3q21-q23 | MRPL3 | Mitochondrial ribosomal protein L3 |
2.33 | 3q26 | SKIL | SKI-like |
2.18 | 3q27-q28 | SIAT1 | “Sialyltransferase 1 (β-galactoside α-2,6-sialyltransferase)” |
2.17 | 3q23-q24 | CLSTN2 | Calsyntenin 2 |
2.00 | 3q21.2 | KIAA1237 | KIAA1237 protein |
NOTE. For all of the genes in this table, the P value associated with the approximate z-test of the chromosome transfer clone expression ratio compared to the parental clone expression ratio was <0.0001. This table shows the summary of genes up- or down-regulated (>2.0 and <0.5, respectively) in the DLD1 + 3 cell line that reside on chromosome 3. The ratio value, chromosome map location, name, and description are given for each gene.