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. 2016 Mar 1;6:22424. doi: 10.1038/srep22424

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Copyright © 2016, Macmillan Publishers Limited

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(A) The sequence including SNP rs1056560 in 3′UTR of CRY1 gene. (B) Relative expression levels of miR-381 and miR-300 in SGC-7901, BGC-823 and HEK-293T cells. (C) The effect of SNP rs1056560 genotypes on the expression of CRY1 gene in SGC-7901, BGC-823 and HEK-293T cells. (D) Relative mRNA expression level of CRY1 gene in 60 GC tissues with different SNP rs1056560 genotypes. Recombinant vector (pMIR-rs1056560-T or pMIR-rs1056560-G) and pTL-TK were co-transfected into SGC-7901, BGC-823 and HEK-293T cells. Data are expressed as mean ± standard deviation (SD) of three independent experiments. Student’s t test was used to examine statistical difference.