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Simulation of residual histamin, PMN, and M Φ. a In silico estimation of residual histamine (solid) and mast cell source (dotted) up to 36 hours. The simulation prediction of recruited PMN while (b) mast cells are treated, (c) H1/H2 histamine receptors are treated after 20 hours, and (d) mast cells are blocked before first 20 hours and H1/H2 histamine receptors are treated after 20 hours. The dotted lines of (b-d) describe the simulation result under normal condition
