Table 1.
State of hormonal receptors in several cell lines used as molecular markers for breast cancer diagnosis
| Cell line | Histological subtype | ER/PRa | HER2b | EGFRc | CK5-6d |
|---|---|---|---|---|---|
| MCF10A | Control | 0 | 0-1+ | 2+ | + |
| MCF-7 | LAe | 6 | 0-1+ | 1+ | - |
| T-47D | LA | >0 | 2+ | - | - |
| ZR-75-1 | LA | 3-4 | 2+ | 1+ | - |
| BT-474 | LBf | 0/8 | 3+ | 1+ | - |
| BT-20 | TNg | 0 | 0-1+ | 2+ | - |
| MB-231 | TN | 0 | 0-1+ | 1+ | - |
| MB-468 | TN | 0 | 0 | 3+ | - |
a ER/PR Estrogen/Progesterone receptor, b HER2 Human epidermal growth factor receptor; c EGFR epidermal growth factor, d CK5-6 Cytokeratin 5/6; e LA luminal A, f LB Luminal B, g TN triple-negative