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. 2016 Feb 29;15:129. doi: 10.1186/s12936-016-1181-1

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© Höglund et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Goodness of fit plots of desethylchloroquine. Plots of the observed versus population predicted concentrations (a) and observed versus individual predicted concentrations (b). Weighed individual residuals versus individual predictions (c) and weighed residuals versus time (d). The black line is a non-parametric smoother describing the trend and the black line is the line of unity