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Working model for how OME and Mx alpha mediate killing. The Mx alpha units that are absent from DK1622 are proposed to contain a toxin-antitoxin system. The toxin is transferred to a target cell by an OME-mediated process. For the toxin to kill, the target cell must express OmrA and lack the antitoxin. Lollipops represent phospholipid molecules; OM, outer membrane; IM, inner membrane. See the text for additional details.
