Skip to main content
. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Biochem J. 2013 Feb 15;450(1):231–242. doi: 10.1042/BJ20121612

Figure 3.

Figure 3

Concentration dependence of oxime reactivation of A) sarin, B) cyclosarin, C) VX and D) paraoxon inhibited (conjugated) hBChE. Dependence for the lead oxime TAB2OH compared to reference cationic oxime 2PAM (measured in triplicate experiments at 37 °C in 0.10M phosphate buffer pH 7.4). Reactivation constants derived for each concentration dependence are given in Table 1. OP conjugates of sarin, cyclosarin and VX were formed by reaction with Flu-MPs and were identical to nerve agent inhibited enzymes (cf. Experimental section).