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Histone modification, DNA methylation, and non-coding RNA alter gene expression pattern. Epigenetic writers catalyze the chemical modifications of amino acids on histones or the cytosine of DNA. Epigenetic erasers catalyze the removal of these modifications and epigenetic readers recognize the modifications and recruit large macromolecular complexes to the chromatin template. Ac, Acetyl; M, Metyl; C, protein complex.
