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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: J Endocrinol. 2015 Dec 23;228(3):179–191. doi: 10.1530/JOE-15-0360

Table 2.

Comparison of pubertal body weight at puberty in Lin28a GOF, Lin28b LOF, and let-7 GOF male and female mice

genotype sex weight at VO/PS n
wt M 15.4 +/− 1.3 33
Lin28a GOF M 20.8 +/− 2.1 16
p<0.0001
wt F 15.3 +/− 1.5 24
Lin28a GOF F 21.1 +/− 2.0 15
p<0.0001
wt M 16.8 +/− 2.0 29
Lin28b LOF M 16.6 +/− 2.1 17
ns
wt F 15.5 +/− 0.8 13
Lin28b LOF F 14.8 +/− 1.3 9
ns
control M 16.5 +/− 1.9 12
let-7 GOF M 18.2 +/− 2.1 15
p=0.03
control F 15.9 +/− 0.8 24
let-7 GOF F 15.3 +/− 1.0 22
p=0.008

VO, vaginal opening. PS, preputial separation. P-values were calculated with the student’s t-test.