Skip to main content
. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Bioessays. 2016 Jan 13;38(3):232–243. doi: 10.1002/bies.201500142

Figure 3.

Figure 3

Potential ATP-dependent mechanisms of subunit exchange. A: An ATP-dependent post-translational modification of an IF tetramer (example illustrated, phosphorylation) induces its dissociation from ULF. Removal of the modification (here by the action of a phosphatase) allows the lateral association of tetramers into ULF. B: ATP-dependent binding of an IF tetramer to a chaperone facilitates its dissociation from a ULF and maintains the tetramer’s solubility. Release of the tetramer from the chaperone (for example via ATP hydrolysis) is necessary for the tetramer to laterally associate into ULF.

HHS Vulnerability Disclosure