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HPV- HNSCC patients with mutated or deleted tumor suppressor genes from The Cancer Genome Atlas.
| Gene | Pathway | % Mutated or Deleted |
|---|---|---|
| TP53 | Cell Cycle | 84% |
| CDKN2A | Cell Cycle | 57% |
| NOTCH1 | Squamous Differentiation | 21% |
| CASP8 | Apoptosis | 10% |
| PTEN | Cell Cycle | 2% |
