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. 2016 Feb 11;352:i276. doi: 10.1136/bmj.i276

Table 3.

Event counts, incidence rates, and incidence rate ratios (95% confidence intervals) for incident cervical cancer by abnormality, follow-up time (years), and histopathology of cancer

0.5-3.5 years 3.5-6.5 years 6.5-10.5 years 10.5-15.5 years
No of cases* IR† IRR (95% CI)‡ No of cases* IR† IRR (95% CI)‡ No of cases* IR† IRR (95% CI)‡ No of cases* IR† IRR (95% CI)‡
All histopathologies
AGC 73 190.8 24.1 (19.1 to 30.5) 26 79.3 10.0 (6.8 to 14.7) 21 58.7 7.4 (4.8 to 11.4) 12 37.9 4.8 (2.7 to 8.5)
HSIL 178 103.9 13.4 (11.5 to 15.6) 58 40.1 5.1 (4.0 to 6.7) 72 45.4 5.8 (4.6 to 7.3) 63 43.6 5.5 (4.3 to 7.1)
LSIL 347 52.9 6.8 (6.1 to 7.6) 193 35.5 4.5 (3.9 to 5.3) 192 33.2 4.2 (3.7 to 4.9) 168 33.4 4.2 (3.6 to 5.0)
Normal Reference Reference Reference Reference
Adenocarcinoma
AGC 53 138.6 60.8 (46.0 to 80.4) 22 67.1 29.0 (19.0 to 44.4) 16 44.7 19.2 (11.7 to 31.5) 7 22.1 9.4 (4.5 to 19.9)
HSIL 25 14.6 6.8 (4.6 to 10.2) 7 4.8 2.2 (1.0 to 4.7) 12 7.6 3.4 (1.9 to 6.0) 11 7.6 3.3 (1.8 to 6.1)
LSIL 44 6.7 3.1 (2.3 to 4.2) 39 7.2 3.3 (2.4 to 4.5) 31 5.4 2.4 (1.7 to 3.4) 30 6 2.6 (1.8 to 3.8)
Normal Reference Reference Reference Reference
Squamous cell cancer
AGC 18 47.1 9.1 (5.7 to 14.5) 4 12.2 2.4 (0.9 to 6.3) 4 11.2 2.2 (0.8 to 5.8) 4 12.6 2.5 (0.9 to 6.7)
HSIL 145 84.6 16.3 (13.7 to 19.4) 47 32.5 6.3 (4.7 to 8.4) 57 36.0 7.0 (5.3 to 9.1) 50 34.6 6.7 (5.1 to 8.9)
LSIL 292 44.5 8.6 (7.6 to 9.8) 147 27.1 5.2 (4.4 to 6.2) 151 26.1 5.1 (4.3 to 6.0) 133 26.4 5.1 (4.3 to 6.1)
Normal Reference Reference Reference Reference

*No of cases of cervical cancer.

†Observed incidence rate, per 100 000 person years.

‡Incidence rate ratio with 95% confidence interval, relative to women with regular normal cytology, adjusted for attained age.