Table 3.
Event counts, incidence rates, and incidence rate ratios (95% confidence intervals) for incident cervical cancer by abnormality, follow-up time (years), and histopathology of cancer
| 0.5-3.5 years | 3.5-6.5 years | 6.5-10.5 years | 10.5-15.5 years | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No of cases* | IR† | IRR (95% CI)‡ | No of cases* | IR† | IRR (95% CI)‡ | No of cases* | IR† | IRR (95% CI)‡ | No of cases* | IR† | IRR (95% CI)‡ | ||||
| All histopathologies | |||||||||||||||
| AGC | 73 | 190.8 | 24.1 (19.1 to 30.5) | 26 | 79.3 | 10.0 (6.8 to 14.7) | 21 | 58.7 | 7.4 (4.8 to 11.4) | 12 | 37.9 | 4.8 (2.7 to 8.5) | |||
| HSIL | 178 | 103.9 | 13.4 (11.5 to 15.6) | 58 | 40.1 | 5.1 (4.0 to 6.7) | 72 | 45.4 | 5.8 (4.6 to 7.3) | 63 | 43.6 | 5.5 (4.3 to 7.1) | |||
| LSIL | 347 | 52.9 | 6.8 (6.1 to 7.6) | 193 | 35.5 | 4.5 (3.9 to 5.3) | 192 | 33.2 | 4.2 (3.7 to 4.9) | 168 | 33.4 | 4.2 (3.6 to 5.0) | |||
| Normal | — | — | Reference | — | — | Reference | — | — | Reference | — | — | Reference | |||
| Adenocarcinoma | |||||||||||||||
| AGC | 53 | 138.6 | 60.8 (46.0 to 80.4) | 22 | 67.1 | 29.0 (19.0 to 44.4) | 16 | 44.7 | 19.2 (11.7 to 31.5) | 7 | 22.1 | 9.4 (4.5 to 19.9) | |||
| HSIL | 25 | 14.6 | 6.8 (4.6 to 10.2) | 7 | 4.8 | 2.2 (1.0 to 4.7) | 12 | 7.6 | 3.4 (1.9 to 6.0) | 11 | 7.6 | 3.3 (1.8 to 6.1) | |||
| LSIL | 44 | 6.7 | 3.1 (2.3 to 4.2) | 39 | 7.2 | 3.3 (2.4 to 4.5) | 31 | 5.4 | 2.4 (1.7 to 3.4) | 30 | 6 | 2.6 (1.8 to 3.8) | |||
| Normal | — | — | Reference | — | — | Reference | — | — | Reference | — | — | Reference | |||
| Squamous cell cancer | |||||||||||||||
| AGC | 18 | 47.1 | 9.1 (5.7 to 14.5) | 4 | 12.2 | 2.4 (0.9 to 6.3) | 4 | 11.2 | 2.2 (0.8 to 5.8) | 4 | 12.6 | 2.5 (0.9 to 6.7) | |||
| HSIL | 145 | 84.6 | 16.3 (13.7 to 19.4) | 47 | 32.5 | 6.3 (4.7 to 8.4) | 57 | 36.0 | 7.0 (5.3 to 9.1) | 50 | 34.6 | 6.7 (5.1 to 8.9) | |||
| LSIL | 292 | 44.5 | 8.6 (7.6 to 9.8) | 147 | 27.1 | 5.2 (4.4 to 6.2) | 151 | 26.1 | 5.1 (4.3 to 6.0) | 133 | 26.4 | 5.1 (4.3 to 6.1) | |||
| Normal | — | — | Reference | — | — | Reference | — | — | Reference | — | — | Reference | |||
*No of cases of cervical cancer.
†Observed incidence rate, per 100 000 person years.
‡Incidence rate ratio with 95% confidence interval, relative to women with regular normal cytology, adjusted for attained age.