Figure 9.

Precursors of neuropeptides in A. rubens that are novel echinoderm representatives of bilaterian neuropeptide families. Predicted signal peptides are shown in blue, putative neuropeptides are shown in red (with cysteine (C) residues underlined), C-terminal glycine (G) residues that are putative substrates for amidation are shown in orange and putative dibasic cleavage sites are shown in green. For the (a) asterotocin and (b) NGFFYamide precursors, the C-terminal neurophysin domain (with the characteristic 14 cysteine (c) residues underlined) is shown in purple.