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Examination of the expression of molecules in the Notch signaling pathway in the forebrain of mice after MW167 and quetiapine treatment. (A-C) RT-PCR showed that the elevated mRNA levels of Notch1, Hes1, and Hes5of quetiapine were inhibited by MW167. (D-H) Western-blot analysis showed the rescue expressions of Hes1 and Hes5 in the quetiapine-treated group were blocked by MW167. **P<.01, #P<.05 compared with CPZ + Que group.
