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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Pharmacol Res. 2015 Dec 30;104:115–123. doi: 10.1016/j.phrs.2015.12.032

Fig. 3.

Fig. 3

The inhibitory effects of Higenamine on apoptotic protein expression were reversed by β2-AR but not β1-AR antagonism. (A) Higenamine (100 μM) dose-dependently decreased cleaved-caspase 9 and 3 proteins stimulated by H2O2 (250 μM for 24 h) in NRVMs. (B) The effects of higenamine were significantly blocked by β2-AR specific antagonist ICI118551 (0.5 μM), but not β1-AR specific antagonist CGP20712a (1 μM). *P<0.05 vs. control; #P<0.05 vs. H2O2 alone; †P<0.05 vs. H2O2 and higenamine. Results were derived from 3 independent experiments.