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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: J Oral Facial Pain Headache. 2015 Fall;29(4):349–362. doi: 10.11607/ofph.1463

Table 4.

Between-Group Brain Activation Comparisons

Brain region Side Cluster size
(voxels)* 		Thresholded
z-score (FE)		 Unthresholded
z-score (ME)		 MNI coordinates (mm)
X Y Z
PDAP > Control stimulus-intensity match
  Inferior parietal lobule Right 11,491 5.95 2.28 67 −26 26
  SII Right - 5.52 2.11 65 −24 22
  SI Right - 4.51 2.41 63 −13 32
  SII Left 10,304 4.76 1.51 −65 −19 10
  Inferior parietal lobule Left - 4.47 1.96 −61 −23 25
  SI Left - 3.91 2.39 −57 −7 37
  Premotor cortex Left - 2.99 2.04 −48 −6 57
  Cerebellum Right 628 3.95 2.19 20 −66 −19
  Insula Right 479 5.07 2.05 43 −3 −12
  Thalamus Right 380 3.1 1.34 12 −16 9
  Middle frontal gyrus (BA 9) Right 312 4.17 2.09 43 44 33
  Middle frontal gyrus (BA 10) Right 305 3.87 2.67 43 52 19
  Insula Left 291 4.04 2.75 −37 −5 −5
  Caudate Left 211 3.68 2.20 −16 4 19
  Frontal orbital cortex Left 177 3.69 2.40 −40 30 −7
  Premotor cortex Right 114 3.38 1.27 47 −15 61
  Superior parietal lobe Right 109 3.51 2.17 36 −44 45
PDAP > Control subjective-pain match
  SII Right 11,621 4.19 1.87 47 −7 6
  Premotor cortex Right 11,365 4.19 2.18 52 9 44
  Inferior frontal gyrus (pars opercularis) Right - 3.81 1.80 51 22 26
  Middle frontal gyrus (BA 9) Right 908 3.82 2.25 41 45 34
  Insula Right 838 3.98 2.37 40 3 −8
  Medial frontal gyrus (BA 8) Right 469 3.65 2.14 4 49 41
  Middle frontal gyrus Right 248 4.05 3.70 51 39 16
  Frontal orbital cortex Left 103 3.59 2.96 −38 30 −7
*

Voxel size = 1 mm3. Reported only clusters with > 100 voxels.

MNI = Montreal Neurological Institute; FE = fixed-effects; ME = mixed-effects; SI = primary somatosensory cortex; SII = secondary somatosensory cortex; BA = Brodmann area; Shadowed rows: maximum activation within the cluster. White rows: local maxima within the cluster listed above it.