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A, The steady-state inactivation levels were measured by using double-pulse protocol. B, Steady-state inactivation curves for the ICaL in the absence and presence of SPX (300 μM). C, Voltage dependence of ICaL activation in the absence and presence of SPX (300 μM). The half-activation voltage was not significantly changed by SPX (n = 10, paired t-test, P > 0.05).
