Table 3. Pkdhfr genotypes among patients enrolled at QEH, Kudat District Hospital and Kota Marudu District Hospital.
Genotype | Frequency | Percent |
---|---|---|
Wild Type* | 304 | 67.71 |
T91P | 42 | 9.35 |
R34L | 40 | 8.91 |
V149A | 17 | 3.79 |
A44T | 6 | 1.34 |
E119V | 6 | 1.34 |
H92Q | 5 | 1.11 |
V52L | 5 | 1.11 |
R34L, V149A | 4 | 0.89 |
T91A, P129Q | 4 | 0.89 |
T91P, D157Y* | 3 | 0.67 |
E77G | 2 | 0.45 |
T91A | 2 | 0.45 |
T91P/A | 1 | 0.22 |
D157Y* | 1 | 0.22 |
D24Y | 1 | 0.22 |
E29K | 1 | 0.22 |
L160F | 1 | 0.22 |
P129Q | 1 | 0.22 |
R34L, D157N* | 1 | 0.22 |
T91P, P129Q | 1 | 0.22 |
V52L, Q108H | 1 | 0.22 |
Total | 449 | 100.00 |
*Indicate genotypes for which corresponding protein structures were not modelled